TY - JOUR AU - Kawakami, Ito AU - Hasegawa, Masato AU - Arai, Tetsuaki AU - Ikeda, Kenji AU - Oshima, Kenichi AU - Niizato, Kazuhiro AU - Aoki, Naoya AU - Omi, Katsuse AU - Higashi, Shinji AU - Hosokawa, Masato AU - Hirayasu, Yoshio AU - Akiyama, Haruhiko PY - 2014 DA - 2014/04/08 TI - Tau accumulation in the nucleus accumbens in tangle-predominant dementia JO - Acta Neuropathologica Communications SP - 40 VL - 2 IS - 1 AB - Tangle-predominant dementia (TPD) is characterized neuropathologically by numerous neurofibrillary tangles in the limbic areas with no or occasional senile plaques throughout the brain. TPD is an under-recognized disease, while it is a common cause of dementia in those over 80 years of age. In the present study, we describe hyperphosphorylated tau (tau) accumulation in the nucleus accumbens (Acb) in patients with TPD. SN - 2051-5960 UR - https://doi.org/10.1186/2051-5960-2-40 DO - 10.1186/2051-5960-2-40 ID - Kawakami2014 ER -