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Table 1 Summary of the characterization of New TDP-43 MAbs

From: Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins

MAb

Isotype

Epitope (aa)

IP

IB

IHC

ICC

ELISA capture

ELISA detect

Human preference

211

IgG1

6-24

-

+

+

+

+

-

-

5031

IgG2a

25-181

+

+

+

+

+

+

-

138

IgG2a

182-261

+

+

+

+

+

+

+

5060

IgG2a

182-261

ND

+

+

+

+

+

-

5117

IgG2a

287-322

ND

+

+

+

+

+

-

5156

IgG2a

287-322

+

+

+

+

+

+

-

205

IgG2a

262-391

+

+

+

+

+

+

+

241

IgG1

262-391

+

+

+

+

+

+

+

5028

IgG1

262-391

+

+

+

+

+

+

-

5032

IgG1

262-391

+

+

+

+

+

+

+

5053

IgG1

262-391

ND

+

+

-

+

+

-

5056

IgG2a

261-391

+

+

+

+

+

+

-

5089

IgG2b

261-391

+

+

+

+

+

+

-

5095

IgG1

261-391

+

+

+

+

+

+

+

5104

IgG1

261-391

+

+

+

+

+

+

+

5123

IgG1

261-391

+

+

+

+

+

+

+

5101

IgG1

261-391

+

+

+

+

+

+

-

5195

IgG2a

394-414

+

+

+

+

+

+

-

  1. This table summarizes the properties the new MAbs described here. New abbreviation: ND = not determined.