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Table 1 Summary of the characterization of New TDP-43 MAbs

From: Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins

MAb Isotype Epitope (aa) IP IB IHC ICC ELISA capture ELISA detect Human preference
211 IgG1 6-24 - + + + + - -
5031 IgG2a 25-181 + + + + + + -
138 IgG2a 182-261 + + + + + + +
5060 IgG2a 182-261 ND + + + + + -
5117 IgG2a 287-322 ND + + + + + -
5156 IgG2a 287-322 + + + + + + -
205 IgG2a 262-391 + + + + + + +
241 IgG1 262-391 + + + + + + +
5028 IgG1 262-391 + + + + + + -
5032 IgG1 262-391 + + + + + + +
5053 IgG1 262-391 ND + + - + + -
5056 IgG2a 261-391 + + + + + + -
5089 IgG2b 261-391 + + + + + + -
5095 IgG1 261-391 + + + + + + +
5104 IgG1 261-391 + + + + + + +
5123 IgG1 261-391 + + + + + + +
5101 IgG1 261-391 + + + + + + -
5195 IgG2a 394-414 + + + + + + -
  1. This table summarizes the properties the new MAbs described here. New abbreviation: ND = not determined.