Table 1 Transmission of dCJD or sCJD to PrP-humanized mice
From: Distinct origins of dura mater graft-associated Creutzfeldt-Jakob disease: past and future problems
Inoculum (ID) | Incubation period in days ± SEM ( n/n 0)a | ||
|---|---|---|---|
| Â | 129Â M/M | 129Â V/V | |
| Â | Tg + Ki-Hu129Â M/Mb | Ki-Hu129M/Mb | Ki-Hu129V/Vb |
|  | (9.8×)c | (1×) | (1×) |
np-dCJD (GF) | 161 ± 5 (5/5) | N.D. d | N.D. |
np-dCJD (TC) | 208 ± 2 (5/5) | N.D. | N.D. |
p-dCJD (KR) | 420 ± 10 (5/5) | 685 ± 51 (5/5) | 259 ± 6 (6/6) |
p-dCJD (KD) | 398 ± 10 (5/5) | 447 ± 51 (6/6) | 317 ± 8 (11/11) |
sCJD-MM1 | 175 ± 4 (9/9) | 467 ± 24 (8/8) | 774 ± 32 (6/6) |
sCJD-VV2 | 505 ± 14 (5/5) | 633 ± 49 (6/6) | 302 ± 9 (7/7) |
sCJD-MV2K | N.D. | 638 ± 57 (4/4) | 329 ± 3 (4/4) |
sCJD-MV2K+C | N.D. | 600 ± 22 (6/6) | 332 ± 15 (4/4) |
129 M/M mouse-passaged sCJD-VV2 | N.D. | 685 ± 17 (6/6) | 309 ± 3 (7/7) |