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Figure 5 | Acta Neuropathologica Communications

Figure 5

From: In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques

Figure 5

Correlations between quantitative parameters of plaque growth dynamics. (a) Plaque formation rate as a function of plaque density. Black line, linear regression (slope is significantly different from zero, p = 0.016). Each circle represents one imaged position. (b) Plaque growth rate as a function of plaque density. Error bars show the 95% CI. Black line shows a linear regression of the data. The slope is statistically significant different from zero (p < 0.001). (c) Radius of newly formed plaques at the end of long-term imaging over 15.5 months as a function of the age of the mouse at plaque formation (N = 81 newly formed plaques from 2 positions). (d) Plaque radius at the end of long-term imaging over 15.5 months as a function of plaque growth rate (N = 90 newly formed and preexisting plaques). Black line shows a linear regression of the data. The slope is statistically significant different from zero. Statistical tests: F-test (a, b, d), Spearman correlation (c).

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