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Table 2 Agreement of biomarker measures for NI and subtle cognitive changes

From: Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition

  aHV SPARE-AD HCI PC-FDG-PET T-tau P-tau181
   (+) (−) (+) (−) (+) (−) (+) (−) (+) (−)
aHV   66.0% 34.0% 56.4% 43.6% 66.1% 33.9% 60.4% 39.6% 55.75% 44.25%
SPARE-AD 0.06   68.5% 31.5% 50.7% 49.3% 79.0% 21.0% 45.3% 54.7%
HCI 0.05 0.05   64.5% 45.5% 63.6% 36.4% 46.0% 54.0%
PC-FDG-PET 0.33 0.03 0.10   50.8% 49.2% 51.0% 49.0%
T-tau 0.06 0.04 0.11 0.07   63.6% 36.4%
P-tau 181 0.15 0.0 −0.01 −0.05 0.31  
  1. Numbers below the diagonal represent Cohen’s kappa index. Numbers above the diagonal represent the percentage of subjects that were classified the same way by the pair of NI biomarkers (+) and the percentage of cases that were classified differently by the pair of NI biomarkers (−).