Figure 5

Identification of a novel complex fusion DHX57:TMEM178:MAP4K3. (a) Affymetrix 500 K SNP array of chromosome 2, highlighting two amplicons, the most telomeric encompassing MYCN, the more centromeric as 2p22.1 involving intragenic breakpoints in DHX57 and TMEM178 (green). (b) Custom oligonucleotide array of the 2p22.1 amplicon, revealing two amplified structures and three intragenic breakpoints, in DHX57, MAP4K3 and TMEM178 (green).