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Table 1 Case characteristics

From: MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies

Case # Brain region Format Gender Age Diagnosis Braak stage PMI (h:m) pH CSF Brain weight (g) ApoE genotype
In situ hybridization         
6 HC FF M 85 NDE I 4:15 6.68 1181 4:4
7 HC FF F 91 NDE I 7:45 6.90 1074 3:3
27 HC FF F 84 AD V 5:55 6.42 1217 3:3
29 HC FF F 89 AD V 4:40 6.28 1022 4:3
19 HC FF F 82 AD VI 4:00 6.66 1110 4:4
21 HC FF F 89 AD VI 4:30 6.35 1185 4:3
Immunohistochemistry/Immunofluorescence       
1 HC FF M 74 NDE 0 8:00 6.75 1317 3:2
22 HC FF F 77 NDE I 5:30 6.74 1343 4:3
4 HC FF M 78 NDE I 6:55 6.42 1332 3:3
30 HC FFPE F 83 NDE I 5:30 6.48 1294 3:2
6 HC FFPE M 85 NDE I 4:15 6.68 1181 4:4
7 HC FFPE, FF F 91 NDE I 7:45 6.90 1074 3:3
9 HC FFPE M 81 NDE II 5:30 6.46 1348 3:3
25 HC FFPE, FF M 87 NDE II 4:55 6.31 1052 3:3
10 HC FFPE M 82 NDE IV 10:00 6.53 1528 4:3
38 HC FF F 95 AD/LBV IV 5:25 6.10 1091 3:3
13 HC FFPE, FF M 64 AD IV 6:00 6.62 1128 3:3
26 HC FF F 86 AD IV 5:05 6.62 998 4:3
31 HC FFPE F 94 AD IV 5:05 6.52 1170 4:3
11 HC FF F 71 AD V 5:30 6.36 1125 4:3
24 HC FF M 75 AD V 5:15 6.39 1178 4:3
32 HC FF F 78 AD V 4:50 6.22 1105 4:4
33 HC FFPE F 82 AD V 4:35 6.49 1104 4:3
14 HC FFPE F 84 AD V 7:15 6.58 1129 4:3
12 HC FF F 84 AD V 4:50 6.67 1092 4:4
28 HC FFPE M 87 AD V 6:10 6.14 1088 3:3
16 HC FF F 88 AD V 5:10 6.62 1075 4:3
29 HC FFPE F 89 AD V 4:40 6.28 1022 4:3
34 HC FFPE F 67 AD VI 5:50 6.75 945 3:3
18 HC FFPE, FF F 68 AD VI 3:50 6.50 1095 3:2
35 HC FFPE F 69 AD VI 4:45 6.33 862 3:3
37 HC FF F 87 AD VI 4:00 6.80 1048 4:3
21 HC FF F 89 AD VI 4:30 6.35 1185 4:3
Western blot          
1 HC FF M 74 NDE 0 8:00 6.75 1317 3:2
4 HC FF M 78 NDE I 6:55 6.42 1332 3:3
6 HC FF M 85 NDE I 4:15 6.68 1181 4:4
7 HC FF F 91 NDE I 7:45 6.90 1074 3:3
27 HC FF F 84 AD V 5:55 6.42 1217 3:3
29 HC FF F 89 AD V 4:40 6.28 1022 4:3
19 HC FF F 82 AD VI 4:00 6.66 1110 4:4
  1. AD = Alzheimer’s disease; FF = fresh frozen; FFPE = formalin-fixed paraffin embedded; HC = hippocampus; LBV = Lewy body variant; NDE = non-demented elderly; PMI = post mortem interval; CSF = cerebrospinal fluid.