Table 1 Case characteristics
Case # | Brain region | Format | Gender | Age | Diagnosis | Braak stage | PMI (h:m) | pH CSF | Brain weight (g) | ApoE genotype |
|---|---|---|---|---|---|---|---|---|---|---|
In situ hybridization | ||||||||||
6 | HC | FF | M | 85 | NDE | I | 4:15 | 6.68 | 1181 | 4:4 |
7 | HC | FF | F | 91 | NDE | I | 7:45 | 6.90 | 1074 | 3:3 |
27 | HC | FF | F | 84 | AD | V | 5:55 | 6.42 | 1217 | 3:3 |
29 | HC | FF | F | 89 | AD | V | 4:40 | 6.28 | 1022 | 4:3 |
19 | HC | FF | F | 82 | AD | VI | 4:00 | 6.66 | 1110 | 4:4 |
21 | HC | FF | F | 89 | AD | VI | 4:30 | 6.35 | 1185 | 4:3 |
Immunohistochemistry/Immunofluorescence | ||||||||||
1 | HC | FF | M | 74 | NDE | 0 | 8:00 | 6.75 | 1317 | 3:2 |
22 | HC | FF | F | 77 | NDE | I | 5:30 | 6.74 | 1343 | 4:3 |
4 | HC | FF | M | 78 | NDE | I | 6:55 | 6.42 | 1332 | 3:3 |
30 | HC | FFPE | F | 83 | NDE | I | 5:30 | 6.48 | 1294 | 3:2 |
6 | HC | FFPE | M | 85 | NDE | I | 4:15 | 6.68 | 1181 | 4:4 |
7 | HC | FFPE, FF | F | 91 | NDE | I | 7:45 | 6.90 | 1074 | 3:3 |
9 | HC | FFPE | M | 81 | NDE | II | 5:30 | 6.46 | 1348 | 3:3 |
25 | HC | FFPE, FF | M | 87 | NDE | II | 4:55 | 6.31 | 1052 | 3:3 |
10 | HC | FFPE | M | 82 | NDE | IV | 10:00 | 6.53 | 1528 | 4:3 |
38 | HC | FF | F | 95 | AD/LBV | IV | 5:25 | 6.10 | 1091 | 3:3 |
13 | HC | FFPE, FF | M | 64 | AD | IV | 6:00 | 6.62 | 1128 | 3:3 |
26 | HC | FF | F | 86 | AD | IV | 5:05 | 6.62 | 998 | 4:3 |
31 | HC | FFPE | F | 94 | AD | IV | 5:05 | 6.52 | 1170 | 4:3 |
11 | HC | FF | F | 71 | AD | V | 5:30 | 6.36 | 1125 | 4:3 |
24 | HC | FF | M | 75 | AD | V | 5:15 | 6.39 | 1178 | 4:3 |
32 | HC | FF | F | 78 | AD | V | 4:50 | 6.22 | 1105 | 4:4 |
33 | HC | FFPE | F | 82 | AD | V | 4:35 | 6.49 | 1104 | 4:3 |
14 | HC | FFPE | F | 84 | AD | V | 7:15 | 6.58 | 1129 | 4:3 |
12 | HC | FF | F | 84 | AD | V | 4:50 | 6.67 | 1092 | 4:4 |
28 | HC | FFPE | M | 87 | AD | V | 6:10 | 6.14 | 1088 | 3:3 |
16 | HC | FF | F | 88 | AD | V | 5:10 | 6.62 | 1075 | 4:3 |
29 | HC | FFPE | F | 89 | AD | V | 4:40 | 6.28 | 1022 | 4:3 |
34 | HC | FFPE | F | 67 | AD | VI | 5:50 | 6.75 | 945 | 3:3 |
18 | HC | FFPE, FF | F | 68 | AD | VI | 3:50 | 6.50 | 1095 | 3:2 |
35 | HC | FFPE | F | 69 | AD | VI | 4:45 | 6.33 | 862 | 3:3 |
37 | HC | FF | F | 87 | AD | VI | 4:00 | 6.80 | 1048 | 4:3 |
21 | HC | FF | F | 89 | AD | VI | 4:30 | 6.35 | 1185 | 4:3 |
Western blot | ||||||||||
1 | HC | FF | M | 74 | NDE | 0 | 8:00 | 6.75 | 1317 | 3:2 |
4 | HC | FF | M | 78 | NDE | I | 6:55 | 6.42 | 1332 | 3:3 |
6 | HC | FF | M | 85 | NDE | I | 4:15 | 6.68 | 1181 | 4:4 |
7 | HC | FF | F | 91 | NDE | I | 7:45 | 6.90 | 1074 | 3:3 |
27 | HC | FF | F | 84 | AD | V | 5:55 | 6.42 | 1217 | 3:3 |
29 | HC | FF | F | 89 | AD | V | 4:40 | 6.28 | 1022 | 4:3 |
19 | HC | FF | F | 82 | AD | VI | 4:00 | 6.66 | 1110 | 4:4 |