Expression of MARK1-3 in hippocampal brain sections. Low magnification micrographs of three adjacent hippocampal sections from an NDE case (#7), with antibodies towards MARK1-3. MARK1 expression is particularly strong in the CA2-layer, with apical dendrites and cell bodies intensely labeled in this area. Less expression is detectable in the CA3, CA4 and DG. MARK2 expression is more homogenously expressed in the CA layers of the hippocampus, particularly strong in CA2 and dentate gyrus (DG), although considerable inter-individual difference existed for this isoform. MARK3 expression on the cytoplasmic level is only detectable in the CA2 layer. Inset images are boxed areas in the CA2 layer. High magnification images are included in Figure 2. Scale bar: 1 mm.