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Figure 2 | Acta Neuropathologica Communications

Figure 2

From: D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma

Figure 2

D -2-hydroxyglutarate levels in FFPE tissue. D-2-hydroxyglutarate levels in FFPE tissue from diffuse astrocytomas and oligodendrogliomas with IDH1 mutations. Shown are the levels of 6 IDH1 wt tumors, 25 with IDH1R132H, 8 with IDH1R132C and 7 with IDH1R132G. All mutant tumors show significant (** = p ≤ 0.01) higher 2-HG levels than wildtype tumors, but only the difference between R132H and R132G mutation was statistically significant (* = p ≤ 0.05).

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Acta Neuropathologica Communications

ISSN: 2051-5960

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