Skip to main content

Table 1 Clinical and radiological data for two morphological groups of ganglioglioma

From: Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups

  Pathology group Age @ diagNosis (years) Gender Dominant site of tumor BRAF: p.V600E BRAF duplication KIAA1549-BRAF fusion gene Neuroimaging
         Midline location Circumscribed Cysts/necrosis Hemorrhage Enhancement Edema Restricted diffusion
GG01 I 6 M Cerebellar hemisphere Yes No No No No 0 0 + + No
GG02 I 9 F Cerebellum Yes No No n/a
GG03 I 21 F Cerebellar hemisphere Yes No No No Yes 0 0 ++ +++ Yes
GG04 I 9 F Medulla Yes No n/a No No 0 0 +++ 0 No
GG05 I 8 F Medulla Yes No n/a No Yes 0 0 ++ 0 n/a
GG06 I 8 M Medulla Yes No n/a No No 0 0 +++ + Yes
GG07 I 15 F MCP Yes No No No No 0 0 +++ ++ No
GG08 I 8 F Cerebellar hemisphere No No No No No +++ 0 + 0 No
GG09 I 11 F MCP No No n/a No Yes 0 0 ++++ 0 n/a
GG10 I 11 F Medulla No No n/a No No 0 0 ++ ++ n/a
GG11 I 12 M Medulla No No No No No 0 0 +++ ++ Yes
GG12 I 1.8 M Pons No No No No No 0 0 + ++ No
GG13 I 21 M MCP No No No No No + 0 +++ + n/a
GG14 I 0.6 M MCP No No No No No 0 0 + + No
GG15 I 15 F Cervico-medullary No No No n/a
GG16 I 14 M Medulla No No No No No 0 0 ++++ ++ No
GG17 II 12 M Vermis No Yes Yes - ex16:ex9 No Yes ++ 0 + 0 Yes
GG18 II 4 F Vermis No Yes Yes - ex15:ex9 Yes Yes + + +++ + Yes
GG19 II 12 F Cord (thoraco-lumbar) No Yes Yes - ex15:ex9 Yes No + + ++ 0 n/a
GG20 II 16 F Cord (cervico-thoracic) No Yes Yes - ex15:ex9 Yes Yes +++ 0 ++ +++ n/a
GG21 II 18 M Cord (cervico-thoracic) No Yes Yes - ex15:ex9 Yes No +++ + + ++++ n/a
GG22 II 9 F Vermis No Yes Yes - ex15:ex9 No Yes ++ 0 +++ ++ No
GG23 II 17 F Vermis No Yes Yes - ex16:ex9 No Yes ++ + + ++ Yes
GG24 II 10 M Cord (cervical) No Yes Yes - ex16:ex11 Yes Yes +++ + ++ ++ n/a
GG25 II 9 M Vermis No Yes Yes - ex16:ex11 Yes No ++++ 0 ++++ + Yes
GG26 II 4 M Medulla No No No No No 0 0 +++ ++ Yes
GG27 II 9 M Midbrain No No No No Yes +++ 0 + ++ n/a
  1. M = male; F = female.
  2. MCP = middle cerebellar peduncle.
  3. n/a = Not available.
  4. 0 - ++++; magnitude scale.