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Figure 1 | Acta Neuropathologica Communications

Figure 1

From: Lipid dysfunction and pathogenesis of multiple system atrophy

Figure 1

A putative model of oligodendrocyte dysfunction in multiple system atrophy. (A) Normal oligodendrocytes with myelin covering the axon of a neuron. (B) Formation of glial cytoplasmic inclusions (GCIs), composed of aggregated α-synuclein, and demyelination. (C) Demyelination is followed by neurodegeneration and cell death.

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