Figure 1From: Lipid dysfunction and pathogenesis of multiple system atrophy A putative model of oligodendrocyte dysfunction in multiple system atrophy. (A) Normal oligodendrocytes with myelin covering the axon of a neuron. (B) Formation of glial cytoplasmic inclusions (GCIs), composed of aggregated α-synuclein, and demyelination. (C) Demyelination is followed by neurodegeneration and cell death.Back to article page