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Table 1 Percent occluded capillary vessels

From: Mechanism of metabolic stroke and spontaneous cerebral hemorrhage in glutaric aciduria type I

  12-hour 24-hour 36-hour 48-hour
Cortex 0% ± 5% 75% ± 10% 45% ± 5% 12% ± 2%
Hippocampus 0% ± 5% 25% ± 5% 80% ± 15% 40% ± 10%
Striatum 0% ± 5% 0% ± 5% 50% ± 8% 90% ± 10%
  1. Semi-thin sections prepared at 12, 24, 36 and 48-hours after initiation of protein diet showed substantial occlusion of capillary vessels in cortex, hippocampus and striatum of Gcdh −/− but not Gcdh−/+ control brain. (n = 6 per time point, all changes significant p < 0.001 compared to control).