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Figure 5 | Acta Neuropathologica Communications

Figure 5

From: Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease

Figure 5

Immunoblot analysis of SphK1, SPL, S1P 1 and IGF-1R. Tissue lysates from frontal cortex (a) and temporal cortex in the hippocampal area (b) of AD and control brains were assayed for SphK1, SPL, S1P1 and IGF-1R expression. Equal loading of protein was monitored using antibody to β-actin. The intensity of each band was quantified using ImageJ software and is provided as representative under corresponding blot. Values are expressed at 1/1000.

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