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Figure 2 | Acta Neuropathologica Communications

Figure 2

From: Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease

Figure 2

Immunohistochemical study of SphK1/SPL expression and Aβ deposits. (a) Double labeling of SphK1 and Aβ in AD brain section from entorhinal cortex. Diffuse and focal deposits are seen in different areas. X200. Inset: Strongly stained neurons (SphK1++, black arrow) and mild stained neurons (SphK1+, white arrow) are clearly distinguishable. X400 (b) Double labeling of SPL and Aβ in AD brain section from entorhinal cortex. A senile plaque is mainly surrounded by strong labeled neurons (SLP++). X400.

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Acta Neuropathologica Communications

ISSN: 2051-5960

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