Table 3 Variants detected within the non-coding region of mtDNA in normal brain tissue (n = 13)

16069

C

T

7.2

D loop - Membrane attachment site, Hypervariable segment 1

16126

T

C

5.2

D loop - Membrane attachment site, Hypervariable segment 1, 7S DNA

16145

G

A

4.8

D loop - Membrane attachment site, Hypervariable segment 1, 7S DNA, termination-associated sequence

16179

C

T

4.3

D loop - Membrane attachment site, Hypervariable segment 1, 7S DNA

16222

C

T

5.1

16261

C

T

9.4

16293

A

G

16.1

16356

T

C

3.0

16519

T

C

57.5

54.5

56.0

57.6

58.3

59.4

D loop - Membrane attachment site, 7S DNA

9

G

T

5.8

10

T

C

5.8

66

G

T

3.2

D-loop - Hypervariable segment 2, membrane attachment site, 7S DNA

73

A

G

6.2

150

C

T

4.4

D loop - Hypervariable segment 2, H-strand origin, Membrane attachment site, 7S DNA

189

A

G

3.0

195

T

C

4.5

D loop - Hypervariable segment 2, H-strand origin, Membrane attachment site

242

C

T

7.7

D loop - Hypervariable segment 2, H-strand origin, mtTF1 binding site, Membrane attachment site

751

A

T

3.9

12s ribosomal RNA (rRNA)

2232

A

T

3.0

16s ribosomal RNA (rRNA)

2647

G

C

12.1

3010

G

A

3.5