TY - JOUR AU - Compston, A. AU - Coles, A. PY - 2008 DA - 2008// TI - Multiple sclerosis JO - Lancet VL - 372 UR - https://doi.org/10.1016/S0140-6736(08)61620-7 DO - 10.1016/S0140-6736(08)61620-7 ID - Compston2008 ER - TY - JOUR AU - Rovaris, M. AU - Confavreux, C. AU - Furlan, R. AU - Kappos, L. AU - Comi, G. AU - Filippi, M. PY - 2006 DA - 2006// TI - Secondary progressive multiple sclerosis: current knowledge and future challenges JO - Lancet Neurol VL - 5 UR - https://doi.org/10.1016/S1474-4422(06)70410-0 DO - 10.1016/S1474-4422(06)70410-0 ID - Rovaris2006 ER - TY - JOUR AU - Confavreux, C. AU - Vukusic, S. PY - 2006 DA - 2006// TI - Age at disability milestones in multiple sclerosis JO - Brain VL - 129 UR - https://doi.org/10.1093/brain/awh714 DO - 10.1093/brain/awh714 ID - Confavreux2006 ER - TY - JOUR AU - Confavreux, C. AU - Vukusic, S. PY - 2006 DA - 2006// TI - Natural history of multiple sclerosis: a unifying concept JO - Brain VL - 129 UR - https://doi.org/10.1093/brain/awl007 DO - 10.1093/brain/awl007 ID - Confavreux2006 ER - TY - JOUR AU - Bjartmar, C. AU - Trapp, B. D. PY - 2001 DA - 2001// TI - Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences JO - Curr Opin Neurol VL - 14 UR - https://doi.org/10.1097/00019052-200106000-00003 DO - 10.1097/00019052-200106000-00003 ID - Bjartmar2001 ER - TY - JOUR AU - Bjartmar, C. AU - Trapp, B. D. PY - 2003 DA - 2003// TI - Axonal degeneration and progressive neurologic disability in multiple sclerosis JO - Neurotox Res VL - 5 UR - https://doi.org/10.1007/BF03033380 DO - 10.1007/BF03033380 ID - Bjartmar2003 ER - TY - JOUR AU - Dutta, R. AU - Trapp, B. D. PY - 2007 DA - 2007// TI - Pathogenesis of axonal and neuronal damage in multiple sclerosis JO - Neurology VL - 68 UR - https://doi.org/10.1212/01.wnl.0000275229.13012.32 DO - 10.1212/01.wnl.0000275229.13012.32 ID - Dutta2007 ER - TY - JOUR AU - Foote, A. K. AU - Blakemore, W. F. PY - 2005 DA - 2005// TI - Inflammation stimulates remyelination in areas of chronic demyelination JO - Brain VL - 128 UR - https://doi.org/10.1093/brain/awh417 DO - 10.1093/brain/awh417 ID - Foote2005 ER - TY - JOUR AU - Ruckh, J. M. AU - Zhao, J. W. AU - Shadrach, J. L. AU - van Wijngaarden, P. AU - Rao, T. N. AU - Wagers, A. J. PY - 2012 DA - 2012// TI - Rejuvenation of regeneration in the aging central nervous system JO - Cell Stem Cell VL - 10 UR - https://doi.org/10.1016/j.stem.2011.11.019 DO - 10.1016/j.stem.2011.11.019 ID - Ruckh2012 ER - TY - JOUR AU - Setzu, A. AU - Lathia, J. D. AU - Zhao, C. AU - Wells, K. AU - Rao, M. S. AU - Ffrench-Constant, C. PY - 2006 DA - 2006// TI - Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells JO - Glia VL - 54 UR - https://doi.org/10.1002/glia.20371 DO - 10.1002/glia.20371 ID - Setzu2006 ER - TY - JOUR AU - Anderson, J. M. AU - Hampton, D. W. AU - Patani, R. AU - Pryce, G. AU - Crowther, R. A. AU - Reynolds, R. PY - 2008 DA - 2008// TI - Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis JO - Brain VL - 131 UR - https://doi.org/10.1093/brain/awn119 DO - 10.1093/brain/awn119 ID - Anderson2008 ER - TY - JOUR AU - Baker, D. AU - O'Neill, J. K. AU - Gschmeissner, S. E. AU - Wilcox, C. E. AU - Butter, C. AU - Turk, J. L. PY - 1990 DA - 1990// TI - Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice JO - J Neuroimmunol VL - 28 UR - https://doi.org/10.1016/0165-5728(90)90019-J DO - 10.1016/0165-5728(90)90019-J ID - Baker1990 ER - TY - JOUR AU - Hampton, D. W. AU - Anderson, J. AU - Pryce, G. AU - Irvine, K. A. AU - Giovannoni, G. AU - Fawcett, J. W. PY - 2008 DA - 2008// TI - An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss JO - J Neuroimmunol VL - 201–202 UR - https://doi.org/10.1016/j.jneuroim.2008.05.034 DO - 10.1016/j.jneuroim.2008.05.034 ID - Hampton2008 ER - TY - JOUR AU - Ludwin, S. K. AU - Sternberger, N. H. PY - 1984 DA - 1984// TI - An immunohistochemical study of myelin proteins during remyelination in the central nervous system JO - Acta Neuropathol VL - 63 UR - https://doi.org/10.1007/BF00685250 DO - 10.1007/BF00685250 ID - Ludwin1984 ER - TY - JOUR AU - Manrique-Hoyos, N. AU - Jürgens, T. AU - Grønborg, M. AU - Kreutzfeldt, M. AU - Schedensack, M. AU - Kuhlmann, T. AU - Schrick, C. AU - Brück, W. AU - Urlaub, H. AU - Simons, M. AU - Merkler, D. PY - 2012 DA - 2012// TI - Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis JO - Ann Neurol VL - 71 UR - https://doi.org/10.1002/ana.22681 DO - 10.1002/ana.22681 ID - Manrique-Hoyos2012 ER - TY - JOUR AU - Petzold, A. AU - Baker, D. AU - Pryce, G. AU - Keir, G. AU - Thompson, E. J. AU - Giovannoni, G. PY - 2003 DA - 2003// TI - Quantification of neurodegeneration by measurement of brain-specific proteins JO - J Neuroimmunol VL - 138 UR - https://doi.org/10.1016/S0165-5728(03)00092-4 DO - 10.1016/S0165-5728(03)00092-4 ID - Petzold2003 ER - TY - JOUR AU - Pryce, G. AU - O'Neill, J. K. AU - Croxford, J. L. AU - Amor, S. AU - Hankey, D. J. AU - East, E. PY - 2005 DA - 2005// TI - Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis JO - J Neuroimmunol VL - 165 UR - https://doi.org/10.1016/j.jneuroim.2005.04.009 DO - 10.1016/j.jneuroim.2005.04.009 ID - Pryce2005 ER - TY - JOUR AU - Smith, P. A. AU - Morris-Downes, M. AU - Heijmans, N. AU - Pryce, G. AU - Arter, E. AU - O'Neill, J. K. PY - 2005 DA - 2005// TI - Epitope spread is not critical for the relapse and progression of MOG 8–21 induced EAE in Biozzi ABH mice JO - J Neuroimmunol VL - 164 UR - https://doi.org/10.1016/j.jneuroim.2005.04.006 DO - 10.1016/j.jneuroim.2005.04.006 ID - Smith2005 ER - TY - JOUR AU - Al-Izki, S. AU - Pryce, G. AU - Jackson, S. J. AU - Giovannoni, G. AU - Baker, D. PY - 2011 DA - 2011// TI - Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis JO - Mult Scler VL - 17 UR - https://doi.org/10.1177/1352458511400476 DO - 10.1177/1352458511400476 ID - Al-Izki2011 ER - TY - JOUR AU - Al-Izki, S. AU - Pryce, G. AU - O'Neill, J. K. AU - Butter, C. AU - Giovannoni, G. AU - Amor, S. AU - Baker, D. PY - 2012 DA - 2012// TI - Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse JO - Mult Scler Rel Dis VL - 1 UR - https://doi.org/10.1016/j.msard.2011.09.001 DO - 10.1016/j.msard.2011.09.001 ID - Al-Izki2012 ER - TY - JOUR AU - Hampton, D. W. AU - Seitz, A. AU - Chen, P. AU - Heber-Katz, E. AU - Fawcett, J. W. PY - 2004 DA - 2004// TI - Altered CNS response to injury in the MRL/MpJ mouse JO - Neuroscience VL - 127 UR - https://doi.org/10.1016/j.neuroscience.2004.05.057 DO - 10.1016/j.neuroscience.2004.05.057 ID - Hampton2004 ER - TY - JOUR AU - Hampton, D. W. AU - Steeves, J. D. AU - Fawcett, J. W. AU - Ramer, M. S. PY - 2007 DA - 2007// TI - Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy JO - Exp Neuro VL - 204 UR - https://doi.org/10.1016/j.expneurol.2006.11.017 DO - 10.1016/j.expneurol.2006.11.017 ID - Hampton2007 ER - TY - JOUR AU - Scott, A. L. AU - Borisoff, J. F. AU - Ramer, M. S. PY - 2005 DA - 2005// TI - Deafferentation and neurotrophin-mediated intraspinal sprouting: a central role for the p75 neurotrophin receptor JO - Eur J Neurosci VL - 21 UR - https://doi.org/10.1111/j.1460-9568.2004.03838.x DO - 10.1111/j.1460-9568.2004.03838.x ID - Scott2005 ER - TY - BOOK AU - Willis, W. D. AU - Coggeshall, R. E. PY - 2004 DA - 2004// TI - Sensory Mechanisms of the Spinal Cord PB - Kluwer Academic/Plenum Publishers CY - New York UR - https://doi.org/10.1007/978-1-4615-0037-7 DO - 10.1007/978-1-4615-0037-7 ID - Willis2004 ER - TY - JOUR AU - Jackson, S. J. AU - Lee, J. AU - Nikodemova, M. AU - Fabry, Z. AU - Duncan, I. D. PY - 2009 DA - 2009// TI - Quantification of myelin and axon pathology during relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse JO - J Neuropathol Exp Neurol VL - 68 UR - https://doi.org/10.1097/NEN.0b013e3181a41d23 DO - 10.1097/NEN.0b013e3181a41d23 ID - Jackson2009 ER - TY - JOUR AU - Hazama, G. I. AU - Yasuhara, O. AU - Morita, H. AU - Aimi, Y. AU - Tooyama, I. AU - Kimura, H. PY - 2005 DA - 2005// TI - Mouse brain IgG-like immunoreactivity: strain-specific occurrence in microglia and biochemical identification of IgG JO - J Comp Neurol VL - 492 UR - https://doi.org/10.1002/cne.20710 DO - 10.1002/cne.20710 ID - Hazama2005 ER - TY - JOUR AU - Szalai, A. J. AU - Barnum, S. R. PY - 2004 DA - 2004// TI - Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis JO - J Neurosci Res VL - 75 UR - https://doi.org/10.1002/jnr.20023 DO - 10.1002/jnr.20023 ID - Szalai2004 ER - TY - JOUR AU - Readnower, R. D. AU - Chavko, M. AU - Adeeb, S. AU - Conroy, M. D. AU - Pauly, J. R. AU - McCarron, R. M. PY - 2010 DA - 2010// TI - Increase in blood–brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury JO - J Neurosci Res VL - 88 UR - https://doi.org/10.1002/jnr.22510 DO - 10.1002/jnr.22510 ID - Readnower2010 ER - TY - JOUR AU - Ryu, J. K. AU - McLarnon, J. G. PY - 2006 DA - 2006// TI - Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood–brain barrier leakiness in amyloid beta-peptide-injected rat hippocampus JO - Exp Neurol VL - 198 UR - https://doi.org/10.1016/j.expneurol.2005.12.016 DO - 10.1016/j.expneurol.2005.12.016 ID - Ryu2006 ER - TY - JOUR AU - Schirmer, L. AU - Albert, M. AU - Buss, A. AU - Schulz-Schaeffer, W. J. AU - Antel, J. P. AU - Brück, W. PY - 2009 DA - 2009// TI - Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord JO - Ann Neurol VL - 66 UR - https://doi.org/10.1002/ana.21799 DO - 10.1002/ana.21799 ID - Schirmer2009 ER - TY - JOUR AU - Vogt, J. AU - Paul, F. AU - Aktas, O. AU - Müller-Wielsch, K. AU - Dörr, J. AU - Dörr, S. PY - 2009 DA - 2009// TI - Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis JO - Ann Neurol VL - 66 UR - https://doi.org/10.1002/ana.21719 DO - 10.1002/ana.21719 ID - Vogt2009 ER - TY - JOUR AU - Coles, A. AU - Deans, J. AU - Compston, A. PY - 2004 DA - 2004// TI - Campath-1H treatment of multiple sclerosis: lessons from the bedside for the bench JO - Clin Neurol Neurosurg VL - 106 UR - https://doi.org/10.1016/j.clineuro.2004.02.013 DO - 10.1016/j.clineuro.2004.02.013 ID - Coles2004 ER - TY - JOUR AU - Coles, A. J. AU - Compston, D. A. AU - Selmaj, K. W. AU - Lake, S. L. AU - Moran, S. AU - Margolin, D. H. PY - 2008 DA - 2008// TI - Alemtuzumab vs. interferon beta-1a in early multiple sclerosis JO - N Engl J Med VL - 359 UR - https://doi.org/10.1056/NEJMoa0802670 DO - 10.1056/NEJMoa0802670 ID - Coles2008 ER - TY - JOUR AU - Bruce, C. C. AU - Zhao, C. AU - Franklin, R. J. PY - 2010 DA - 2010// TI - Remyelination - An effective means of neuroprotection JO - Horm Behav VL - 57 UR - https://doi.org/10.1016/j.yhbeh.2009.06.004 DO - 10.1016/j.yhbeh.2009.06.004 ID - Bruce2010 ER - TY - JOUR AU - Franklin, R. J. AU - Ffrench-Constant, C. AU - Edgar, J. M. AU - Smith, K. J. PY - 2012 DA - 2012// TI - Neuroprotection and repair in multiple sclerosis JO - Nat Rev Neurol VL - 8 UR - https://doi.org/10.1038/nrneurol.2012.200 DO - 10.1038/nrneurol.2012.200 ID - Franklin2012 ER - TY - JOUR AU - Irvine, K. A. AU - Blakemore, W. F. PY - 2008 DA - 2008// TI - Remyelination protects axons from demyelination- associated axon degeneration JO - Brain VL - 131 UR - https://doi.org/10.1093/brain/awn080 DO - 10.1093/brain/awn080 ID - Irvine2008 ER - TY - JOUR AU - Hampton, D. W. AU - Innes, N. AU - Merkler, D. AU - Zhao, C. AU - Franklin, R. J. AU - Chandran, S. PY - 2012 DA - 2012// TI - Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency JO - Am J Pathol VL - 180 UR - https://doi.org/10.1016/j.ajpath.2012.01.018 DO - 10.1016/j.ajpath.2012.01.018 ID - Hampton2012 ER - TY - JOUR AU - Shen, S. AU - Sandoval, J. AU - Swiss, V. A. AU - Li, J. AU - Dupree, J. AU - Franklin, R. J. AU - Casaccia-Bonnefil, P. PY - 2008 DA - 2008// TI - Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency JO - Nat Neurosci VL - 11 UR - https://doi.org/10.1038/nn.2172 DO - 10.1038/nn.2172 ID - Shen2008 ER - TY - JOUR AU - Shields, S. AU - Gilson, J. AU - Blakemore, W. AU - Franklin, R. PY - 1999 DA - 1999// TI - Remyelination occurs as extensively but more slowly in old rats compared to young rats following fliotoxin-induced CNS demyelination JO - Glia VL - 28 UR - https://doi.org/3.0.CO;2-F DO - 3.0.CO;2-F ID - Shields1999 ER -