Figure 7
Regional distribution of filamentous PrP in a brain with A117V mutation. (Case #17): the intensity of the white matter filaments is represented in shades of red, the most intense representing a strong deposition (frontal, parietal and temporal brain) and there is a decreasing gradient towards the posterior lobes, the cerebellum and the brain stem, where fewer filaments were observed. The corresponding semi-quantitative evaluation is listed in Table 6.