The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice

Table 1 Determinations of the parameters employed for quantification of mitochondrial alterations in neurites and nerve cell somata

Percentage of altered mitochondria in nerve cell somata =	$\frac{(\sum area of altered mitochondria within nerve cell somata)}{\sum area of all mitochondria within nerve cell somata} \times 100$
Percentage of altered mitochondria in neurites (axons and dendrites) =	$\frac{(\sum area of altered mitochondria within neurites) \times 100}{\sum area of all mitochondria within neurites}$
Mitochondrial volume density in the nerve cell somata =	$\frac{(\sum area of all mitochondria within nerve cell somata) \times 100}{\sum area of nerve cell somata}$
Mitochondrial volume density in neurites =	$\frac{(\sum area of all mitochondria within neurites) \times 100}{\sum area of neurites}$
Volume density of altered mitochondria in the nerve cell somata =	$\frac{(\sum area of altered mitochondria within nerve cell somata) \times 100}{\sum area of nerve cell somata}$
Volume density of altered mitochondria in neurites =	$\frac{(\sum area of altered mitchondria within neurites) \times 100}{\sum area of neurites}$

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