Table 1 Determinations of the parameters employed for quantification of mitochondrial alterations in neurites and nerve cell somata

Percentage of altered mitochondria in nerve cell somata =

$\frac{\left({\displaystyle \sum \mathit{area}\mathit{of}\mathit{altered}\mathit{mitochondria}\mathit{within}\mathit{nerve}\mathit{cell}\mathit{somata}}\right)}{{\displaystyle \sum \mathit{area}\mathit{of}\mathit{all}\mathit{mitochondria}\mathit{within}\mathit{nerve}\mathit{cell}\mathit{somata}}}\times 100$

Percentage of altered mitochondria in neurites (axons and dendrites) =

$\frac{\left({\displaystyle \sum \mathit{area}\mathit{of}\mathit{altered}\mathit{mitochondria}\mathit{within}\mathit{neurites}}\right)\times 100}{{\displaystyle \sum \mathit{area}\mathit{of}\mathit{all}\mathit{mitochondria}\mathit{within}\mathit{neurites}}}$

Mitochondrial volume density in the nerve cell somata =

$\frac{\left({\displaystyle \sum \mathit{area}\mathit{of}\mathit{all}\mathit{mitochondria}\mathit{within}\mathit{nerve}\mathit{cell}\mathit{somata}}\right)\times 100}{{\displaystyle \sum \mathit{area}\mathit{of}\mathit{nerve}\mathit{cell}\mathit{somata}}}$

Mitochondrial volume density in neurites =

$\frac{\left({\displaystyle \sum \mathit{area}\mathit{of}\mathit{all}\mathit{mitochondria}\mathit{within}\mathit{neurites}}\right)\times 100}{{\displaystyle \sum \mathit{area}\mathit{of}\mathit{neurites}}}$

Volume density of altered mitochondria in the nerve cell somata =

$\frac{\left({\displaystyle \sum \mathit{area}\mathit{of}\mathit{altered}\mathit{mitochondria}\mathit{within}\mathit{nerve}\mathit{cell}\mathit{somata}}\right)\times 100}{{\displaystyle \sum \mathit{area}\mathit{of}\mathit{nerve}\mathit{cell}\mathit{somata}}}$

Volume density of altered mitochondria in neurites =

$\frac{\left({\displaystyle \sum \mathit{area}\mathit{of}\mathit{altered}\mathit{mitchondria}\mathit{within}\mathit{neurites}}\right)\times 100}{{\displaystyle \sum \mathit{area}\mathit{of}\mathit{neurites}}}$