Figure 4
From: Brains from non-Alzheimer’s individuals containing amyloid deposits accelerate Aβ deposition in vivo
APP Swe /PSEN1 ∆E9 mice inoculated with AD and MCI extracts display higher Aβ deposition in the hippocampus. (a) Representative pictures of the deposits stained with the 4G8 antibody in the hippocampus of experimental and control animals (n = 5-8). (b) Magnification of the labeled regions (corpus callosum) in the pictures shown in (a). The scale bar corresponds to 250 μm in (a) and 100 μm in (b). Image analysis was done to quantify the burden of amyloid deposits in the hippocampal area in each group (c). The Aβ deposition was compared among all control and experimental groups.