Skip to main content

Table 1 Demographic, maternal, and neonatal clinical data

From: Cerebellar hemorrhagic injury in premature infants occurs during a vulnerable developmental period and is associated with wider neuropathology

  CHI Control p value
Demographics    
Gender: Female (8/19) 42% (10/26) 38% 0.8053
Gender: Male (11/19) 58% (16/26) 62%  
Gestational Age (weeks) 24.98 (2.41) 25.88 (2.29) 0.1318
Postnatal Age (weeks) 2.96 (2.71) 2.88 (3.01) 0.6789
Postconceptional Age (weeks) 27.83 (3.50) 28.81 (3.17) 0.3362
Race: African-American (6/17) 35% (9/24) 38% 1.0
Race: Caucasian (10/17) 59% (14/24) 58%  
Race: Biracial (1/17) 6% (1/24) 4%  
Birth weight (gm) 746.21 (255.16) 808.54 (228.71) 0.1383
Birth length (cm) 31.91 (3.03) 34.02 (4.07) 0.0376
Birth head circumference (cm) 22.79 (2.57) 23.26 (2.46) 0.5039
Apgar 1 minute 3.53 (2.29) 3.5 (2.34) 0.8701
Apgar 5 minutes 5.12 (2.23) 5.62 (2.40) 0.4593
Postmortem body weight (gm) 1,203.74 (493.93) 1,209.72 (496.38) 0.9683
Postmortem body length (cm) 34.08 (3.04) 35.0 (4.51) 0.4475
Postmortem head circumference (cm) 24.95 (3.31) 25.20 (2.97) 0.7864
Postmortem brain weight, fixed (gm) 115.47 (36.89) 131.77 (41.54) 0.1909
Maternal Factors    
Maternal Age (years) 24.68 (4.41) 26.12 (7.02) 0.407
Pregnancy induced hypertension (3/19) 16% (1/26) 4% 0.2954
Pre-ecclampsia/ecclampsia (1/19) 5% (2/24) 8% 1.0
Maternal infection/antibiotics (9/19) 47% (12/26) 46% 0.9357
Preterm labor (16/19) 84% (26/26) 100% 0.909
Prolonged rupture of membranes (5/19) 26% (7/26) 27% 0.9637
Chorioamnionitis (6/19) 32% (8/26) 31% 0.9538
Multiple gestation (4/19) 21% (7/26) 27% 0.7363
Abruption (7/19) 37% (5/26) 19% 0.1870
Prenatal steroids (15/19) 79% (18/26) 69% 0.4666
Neonatal Course    
Cesarean section (8/19) 42% (18/26) 69% 0.0688
Emergent delivery (11/19) 58% (18/26) 69% 0.4327
Surfactant (19/19) 100% (25/26) 96% 1.0
iNO (6/19) 32% (7/26) 27% 0.7341
Chest compressions and/or epinephrine (5/19) 26% (3/26) 12% 0.2528
Mechanical ventilation (19/19) 100% (26/26) 100% 1.0
Positive pressure ventilation (PPV) and intubation (19/19) 100% (25/26) 96% 1.0
High frequency oscillatory ventilation (HFOV) (14/19) 74% (17/26) 65% 0.5525
Continuous positive airway pressure (CPAP)/nasal cannula (9/19) 47% (14/26) 54% 0.6677
Hypoxia (19/19) 100% (3/26) 12% 0.2515
Pneumonia (6/19) 32% (5/26) 19% 0.4851
Respiratory distress syndrome (RDS) (19/19) 100% (25/26) 96% 1.0
Bronchopulmonary dysplasia (BPD) (5/19) 26% (8/26) 31% 0.7448
Pneumothorax (2/19) 11% (7/26) 27% 0.2644
Pulmonary hemorrhage (8/19) 41% (3/26) 12% 0.0333
PDA on ultrasound (11/17) 65% (11/21) 53% 0.4442
Indomethacin prophylaxis (14/19) 74% (17/26) 65% 0.5525
Ibuprofen/indomethacin (0/19) 0% (4/26) 15% 0.1264
Surgical ligation of PDA (3/19) 16% (1/26) 4% 0.2954
Vasopressors (19/19) 100% (23/26) 88% 0.2515
Hydrocortisone (13/19) 68% (13/26) 50% 0.2166
Volume expanders (19/19) 100% (24/26) 92% 0.5010
Blood transfusion (19/19) 100% (25/26) 96% 1.0
Hyperbilirubinemia (18/18) 100% (23/24) 96% 1.0
Disseminated intravascular coagulation (11/19) 58% (10/26) 38% 0.1968
Sepsis (17/19) 89% (15/26) 58% 0.0152
Meningitis (0/19) 0% (0/26) 0% 1.0
Intestinal injury (10/19) 53% (12/26) 46% 0.6677
Surgery (9/19) 47% (8/26) 31% 0.3532
Feeds (12/19) 63% (15/26) 58% 0.7660
Total parental nutrition (19/19) 100% (26/26) 100% 1.0
Bicarbonate administered (19/19) 100% (25/26) 96% 1.0
Acidosis (pH < 7.20) (19/19) 100% (26/26) 100% 1.0
Renal failure (14/19) 74% (11/26) 42% 0.0339
Furosamide (9/19) 47% (11/26) 42% 0.7358
Pain/sedation medications (19/19) 100% (22/26) 85% 0.1264
Seizures (5/19) 26% (7/26) 27% 0.9637
  1. Data reported as percentages for categorical variables. For continuous variables data are reported as mean and (standard deviation). p values in bold denote statistical significance.