Identification of peptide candidates that may block TDP-43 binding to itself using the high density peptide array. TDP-43 protein associates with TDP-43 membrane at specific regions. Control, binding of the antibody only to the TDP-43 membrane; TDP-43, The TDP-43 membrane was incubated with TDP-43 protein (three repeats). The schematic representation shows the five peptide candidates labeled on the membranes. The peptides were designed based on the identified regions of the membrane to which purified TDP-43 bound.