Figure 5

Terminal deletion in the distal short arm of chromosome 1. Microarray analysis showed a single-copy loss of 34 BAC clones from 1p36.3, spanning approximately 6.8 Mb, with break point between RP1-126A5 and RP3-438 L4. Probes are arranged with the most distal p-arm clones on the left. The blue tracing shows array comparative genomic hybridization data from the first microarray slide (reference Cy5/patient Cy3). The pink tracing shows data from the second microarray slide in which the dyes have been reversed (patient Cy5/reference Cy3). A subset of genes involved in neural development or function are indicated at their approximate position in the deleted region.