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Table 2 Relative miRNA levels in SALS compared to the mean expression in healthy controls

From: Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis

miRNA

Fold change SALS (mean ± S.E.M.)

CSF

Serum

miR-9-5p

0.95 ± 0.06

p = 0.466

1.04 ± 0.07

p = 0.837

miR-132-5p

0.70 ± 0.07

p= 0.047

0.72 ± 0.08

p= 0.025

miR-132-3p

0.76 ± 0.10

p= 0.026

0.66 ± 0.06

p= 0.049

miR-143-5p

1.50 ± 0.22

p= 0.047

0.72 ± 0.08

p= 0.048

miR-143-3p

0.70 ± 0.08

p= 0.006

0.66 ± 0.08

p= 0.015

miR-574-5p

1.51 ± 0.23

p= 0.035

1.03 ± 0.24

p = 0.238

miR-574-3p

0.84 ± 0.19

p = 0.433

0.95 ± 0.17

p = 0.438

miR-558-3p

0.96 ± 0.08

p = 0.754

0.91 ± 0.07

p = 0.364

miR-663a

1.11 ± 0.14

p = 0.826

0.99 ± 0.13

p = 0.914

let-7b

0.76 ± 0.13

p = 0.090

0.60 ± 0.05

p= 0.033

  1. Statistical significant differences are highlighted in bold.