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Table 1 Immunoreactivity in human MS Lesions

From: Endogenously regulated Dab2 worsens inflammatory injury in experimental autoimmune encephalomyelitis

 

Marker (μ ± SD)

Lesion type

Dab2 +ve cells2

CD68 +ve cells

APP +ve elements

Early active – biopsy 1

129.9 ± 25.5

164.1 ±28.3

24.2 ± 5.8

Early active – biopsy 2

86.4 ± 7.7

96.9 ± 12.3

23 ± 4.2

Late active – biopsy 3

10.1 ± 4.1

96.9 ± 19.7

4.9 ± 3.6

Chronic active – autopsy 1

0.64 ± 1.0

58.7 ± 15.8

4.2 ± 1.9

Chronic active – autopsy 2

0.20 ± 0.42

14.0 ± 4.1

2.6 ± 0.97

Chronic active – autopsy 3

0.10 ± 0.32

12.8 ± 4.1

1.8 ± 1.2

  1. Table 1 summarizes Dab2, CD68 and APP positive cell density in serial sections of lesions obtained from biopsy or autopsy specimens.