Characterization of Dab2 expression within MS lesions. Immunohistochemical staining of an early acitve lesion (biopsy) and a chronic active lesion. a/b: Luxol Fast Blue/Periodic Acid Schiff stain showing regions of demyelination (pink). c/d: Staining for the macrophage/microglial marker CD68 (brown) showing large numbers of macrophages throughtout both lesion types. e/f: Dab2 staining in the early acitve and chronic active lesion. e: Dab2 staining can be seen throughout the early active lesion expressed by cells of a macrophage morphology. f: Very little perivenular Dab2 staining (arrows) can be found in the chronic active lesion.