Figure 2
From: Endogenously regulated Dab2 worsens inflammatory injury in experimental autoimmune encephalomyelitis
Characterization of Dab2 expression within the EAE spinal cord. Immunoflourescent staining for Dab2 in the lumbar expansion in an EAE grade 3.0 C57B/6 wild-type mouse spinal cord. Representative confocal images show a: Dual epifluorescence image showing that the vast majority of CD11b-positive macrophages/microglia also stain positively for Dab2. Dab2-negative microglia (arrowhead). b: Dual epifluoresence image showing that a large proportion of GFAP-positive astrocytes also stain positively for Dab2 (arrows). c: Dual epifluoresence image showing that CD3-positive T-lymphocytes do not express Dab2 within inflammatory infiltrates. Scale bars represent 50 μm.