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Figure 1 | Acta Neuropathologica Communications

Figure 1

From: MCP-1/CCR2 signaling-mediated astrocytosis is accelerated in a transgenic mouse model of SOD1-mutated familial ALS

Figure 1

RT-qPCR analysis for MCP-1 and CCR2 mRNA in the spinal cord of mice. MCP-1 (a) and CCR2 (b) mRNA levels normalized with GAPDH mRNA levels are compared between SJL (gray columns) and G1H+/− (black columns) mice sacrificed at presymptomatic (9 w), onset (12 w), and postsymptomatic (15 w) stages (n = 6 in each group). Two-way ANOVA provides P < 0.05. Posthoc Bonferroni correction provides #P < 0.05 and $P < 0.01 as compared to the presymptomatic and onset G1H+/− groups and *P < 0.01 and P < 0.001 as compared to the age-matched SJL groups.

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