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Table 1 D-2HG and αKG levels in individual spots in sections of othotopic xenografts carrying the IDH1-R132H mutation (italic) or wild-type IDH

From: Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG

Spot number D-2-HG (μg/g) α-KG (μg/g)
1 0.0 0
2 4.7 11.2
3 2.9 5.2
4 6.5 17.2
5 4.7 5.2
6 8.3 11.2
7 4.7 17.2
8 66.7 52.9
9 311 35
10 819.8 0
11 653.9 17.2
53 650.2 17.2
54 194.3 5.2
14 0 0
15 0 5.2
18 358.4 17.2
17 254.5 17.2
16 312.9 5.2
19 4.7 23.1
20 6.5 5.2
21 37.5 41
22 63 82.7
23 39.3 41
24 4.7 5.2
25 4.7 17.2
26 6.5 17.2
27 15.6 11.2
28 46.6 35
29 17.4 17.2
30 88.6 52.9
  1. Spots 1-6 represent normal brain.