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Table 3 Impact value of ALDH1 and CD34 IHC for the diagnosis of meningeal SFT or HPC versus meningioma

From: ALDH1 is an immunohistochemical diagnostic marker for solitary fibrous tumours and haemangiopericytomas of the meninges emerging from gene profiling study

  SE CI 95% SP IC 95% PPV IC 95% NPV IC 95%
ALDH1         
TFS n = 25 84% 0.63-0.94 98.8% 0.95-0.99 91.3% 0.7-0.98 97.6% 0.93-0.99
HPC = 55 85.4% 0.73-0.93 98.7% 0.95-0.99 95.9% 0.84-0.99 95.2% 0.9-0.97
CD34         
TFS n = 25 92% 0.72-0.98 95% 0.9-0.97 74.2% 0.55-0.87 98.7% 0.94-0.99
HPC n = 55 74.5% 0.61-0.85 95% 0.9-0.97 83.7% 0.69-0.92 91.7% 0.86-0.95
ALDH1 and CD34+         
TFS n = 20 80% 0.58-0.92 100% 0.97-1 100% 0.79-1 97% 0.93-0.99
HPC n = 34 62% 0.48-0.74 100% 0.97-1 100% 0.87-1 88% 0.83-0.93
  1. SE: sensitivity, PPV: positive predictive value.
  2. SP: specificity, NPV: negative positive value.