Table 3 Impact value of ALDH1 and CD34 IHC for the diagnosis of meningeal SFT or HPC versus meningioma
SE | CI 95% | SP | IC 95% | PPV | IC 95% | NPV | IC 95% | |
|---|---|---|---|---|---|---|---|---|
ALDH1 | ||||||||
TFS n = 25 | 84% | 0.63-0.94 | 98.8% | 0.95-0.99 | 91.3% | 0.7-0.98 | 97.6% | 0.93-0.99 |
HPC = 55 | 85.4% | 0.73-0.93 | 98.7% | 0.95-0.99 | 95.9% | 0.84-0.99 | 95.2% | 0.9-0.97 |
CD34 | ||||||||
TFS n = 25 | 92% | 0.72-0.98 | 95% | 0.9-0.97 | 74.2% | 0.55-0.87 | 98.7% | 0.94-0.99 |
HPC n = 55 | 74.5% | 0.61-0.85 | 95% | 0.9-0.97 | 83.7% | 0.69-0.92 | 91.7% | 0.86-0.95 |
ALDH1 and CD34+ | ||||||||
TFS n = 20 | 80% | 0.58-0.92 | 100% | 0.97-1 | 100% | 0.79-1 | 97% | 0.93-0.99 |
HPC n = 34 | 62% | 0.48-0.74 | 100% | 0.97-1 | 100% | 0.87-1 | 88% | 0.83-0.93 |