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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Extracellular vesicle encapsulated nicotinamide delivered via a trans-scleral route provides retinal ganglion cell neuroprotection

Fig. 3

Mouse retinal explant model in four groups (control, NAM, EV, and NAM-EV). A Schematic illustration of mouse retinal explant and culture method. B Division into four groups based on the presence or absence of additives in the media: control (3DEV), NAM, EV, and NAM-EV, respectively (16 retinas from 8 mice). C Representative images of dendritic arbourisation in each group. Scale bar = 50 μm. D Sholl analysis graphs for each group show significant preservation of dendritic arbour in the NAM and NAM-EV groups compared to the control group (3DEV). DEV days ex vivo. *p < 0.05, All comparison was performed between each treated group and control group (3DEV)

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