Fig. 7
Effect of LXB4 treatment on lipoxin pathway in human brain astrocytes. (A) Astrocyte reactivity genes analyzed by qPCR. The results were normalized to GAPDH. Data are presented as the mean ± SEM, n = 3–4. (B) Representative immunofluorescence images of LCN2 and 5-LOX. Nuclei were labeled with DAPI. (C) LC‒MS/MS-based lipidomic quantification of endogenous lipid mediators, n = 4–5. (Ctrl-untreated control astrocytes, RA- reactive astrocytes). *p < 0.05, **p < 0.01, ***p < 0.001