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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Dysregulation of neuroprotective lipoxin pathway in astrocytes in response to cytokines and ocular hypertension​

Fig. 1

Expression of lipoxin pathway in mouse retina and optic nerve. (A) Representative images of RNAscope ISH (red) (indicated with white arrows) of retina and optic nerve using mRNA probes for Alox5, Alox15, and Fpr2. Nuclei were labeled with DAPI to distinguish nuclear layers of the retina. All images were obtained using a 40x objective. Scale bar = 50 μm. (n = 3). Labels: ganglion cell layer (GCL), inner nuclear layer (INL), outer nuclear layer (ONL). (B) Bar graphs represent the quantification of RNAscope images performed by Qupath software. (C) Bar graphs represent Ct values of lipoxin pathway genes in retinal astrocytes and optic nerves analyzed by qPCR (n = 3)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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