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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Personalized identification and characterization of genome-wide gene expression differences between patient-matched intracranial and extracranial melanoma metastasis pairs

Fig. 7

Survival analysis of melanoma patients from TCGA based on candidate genes that differed in their expression between intra- and extracranial metastasis pairs. Kaplan-Meier curves show differences in survival between melanoma patients from TCGA in the first quartile (blue line, low expression group) and the fourth quartile (red line, high expression group) based on the expression of the specific candidate gene across all TCGA melanoma patients. Differences in survival were statistically tested using the log-rank test and adjusted for multiple testing across all 38 gene candidates by computing FDR-adjusted p-values (q-values). Only significant results are shown (FDR-adjusted p-value: q < 0.1)

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