Fig. 5

DNA methylation status of the three cases. A Table indicating methylation classes and calibrated scores obtained at the DKFZ classifier of Case 1, 2 and 3. B t-SNE plot indicating DNA methylation status of diffuse midline glioma, H3 K27-altered (DMG_K27; n = 20), diffuse hemispheric glioma, H3 G34-mutant (DHG_G34; n = 20), glioblastoma, IDH-wildtype (GBM_RTK1; n = 62, GBM_RTK2; n = 143) and pediatric-type high-grade diffuse gliomas (pHGGs), IDH-wildtype and H3 wildtype (pHGG_MYCN; n = 20 pHGG_RTK1; n = 20 and pHGG_RTK2; n = 20) including Case 1 (red), Case 2 (orange), and Case 3 (yellow)