Fig. 3

Gene mutations, copy number alterations, and chromosomal alterations in the three cases. WES data and methylation classifier data were used for mutation analysis and CNV analysis, respectively. Gene mutations (green box), focal gene amplification (red square), and homozygous deletion (blue square) of cyclins/Rb-related genes, mismatch repair genes, TP53-related genes, RTK/Ras/PI3K/AKT genes, chromatin modifiers, histone H3, IDH, and chromosomal alterations (1p/19q codeletion and chromosome 7 gain and 10 loss) in Case 1 (left), Case 2 (middle), and Case 3 (right). Right bar graph indicates the number of cases exhibiting alterations