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Fig. 9 | Acta Neuropathologica Communications

Fig. 9

From: CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology

Fig. 9

CD206+ and Ly6G+ cell quantification in IA walls of PBS and CLO-treated mice. a Representative image of CAM accumulation in PBS-treated mice. b Representative image of CAM absence in CLO-treated mice. c Quantification of CAM number around the IA vessel wall and the contra arteries at Day5 post-aneurysm induction (N = 4 CLO-treated mice, n = 7 IAs/n = 6 contra arteries. N = 4 PBS-treated mice, n = 16 IAs/n = 7 contra arteries). d Representative image of neutrophil accumulation in PBS-treated mice. e Representative image of the reduced neutrophil number in CLO-treated mice. f Quantification of neutrophil number in the IA vessel wall at Day5 post-aneurysm induction (N = 4 CLO-treated mice, n = 5 IAs/n = 5 contra arteries. N = 4 PBS-treated mice, n = 14 IAs/n = 8 contra arteries. *P < 0.05, **P < 0.01, two-way ANOVA. Scale bar: 100 μm). Statistical analysis was performed using two-way analysis of variance (ANOVA) with post hoc Dunnett adjustment. Further detailed information on statistics is provided in the Methods and Materials

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