Fig. 2

Neocortical distribution of Pick bodies in bvFTD vs PPA. Height of bars represent mean density per cubic millimeter of Pick bodies in neocortical regions in bvFTD (N = 9) and PPA (N = 9) cases. Error bars represent standard errors of mean (SEM). Pick body density was highest in MFG in bvFTD and ATL in PPA, and OCC showed no Pick bodies in bvFTD and PPA. bvFTD displayed generally bilateral distribution of PiD pathology, except for STG which showed rightward asymmetry (p < 0.05). In PPA, regions were generally leftward asymmetric, which reached significance in STG (p < 0.01). ATL showed slight rightward predilection in PPA. MFG = Middle frontal gyrus; STG = Superior temporal gyrus; IPL = Inferior parietal lobule; ATL = Anterior temporal lobe; OCC = Occipital cortex. *p < 0.05; **p < 0.01