Fig. 1
From: Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias
Bilateral and mean total (L + R) neocortical densities of Pick bodies in bvFTD and PPA. Bars represent mean density per cubic millimeter of Pick bodies in neocortical regions in bvFTD (N = 9) and PPA cases (N = 9). Neocortical regions include bilateral middle frontal, superior temporal, and inferior parietal gyri. Error bars represent standard errors of mean (SEM). A Bar graphs demonstrate hemispheric differences in mean neocortical density of Pick bodies, highlighting that right hemispheric neocortex in PPA has significantly fewer Pick bodies than the left hemisphere (p < 0.01). B Bar graphs show the mean overall (L + R) cortical regions in bvFTD vs PPA with error bars representing SEMs. Across the three neocortical regions, bvFTD has significantly greater overall mean density of PiD pathology (M = 25,240.24, SD = 11,431.51) compared to PPA (M = 20,260.76, SD = 11,816.51) (p < 0.01), driven by the leftward asymmetry seen in PPA, as shown in A. **p < 0.01