Fig. 5
From: Loss of Sarm1 reduces retinal ganglion cell loss in chronic glaucoma
Quantitation of RGC density in eyes of B6 and Sarm1 KO mice. A Whole mounted mouse retina following immunohistochemical staining with RBPMS antibody to indicate RGC (green). B Sampling scheme to determine RGC counts in each eye. Data from areas 1, 2, 7, 8, 13, 14, 19, and 20 are averaged to indicate RGC density in the retinal periphery. Images 3, 4, 9, 10, 15, 16, 21, and 22 represent the mid-peripheral area of the retina. Images 5, 6, 11, 13, 17, 18, 23, and 24 represent the central section of the retina. Size of each image equals 330 × 438 μm or 0.1445 mm2. C RGC density in each area of the retina after 16 weeks of elevated IOP (B6 OHT, Sarm1 OHT) and in sham injected controls (B6 control, Sarm1 control). *p \(\le\) 0.05, **p \(\le\) 0.01, ***p \(\le\) 0.001, ****p \(\le\) 0.0001, ns = not significant