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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Fig. 6

Microglial response to Aβ. A Aβ, TREM2 and Iba-1 immunostaining of brain tissue from 18-months-old tg-UppSwe, tg-ArcSwe and tg-Swe mice. Scale bar: 100 µm. ELISA quantification of soluble TREM2 in TBS16K (B) and TBS-T (C) brain extracts from 18-months-old wt, tg-UppSwe, tg-ArcSwe and tg-Swe mice. Not significant (ns), *P < 0.05, **P < 0.01, ***P < 0.001

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Acta Neuropathologica Communications

ISSN: 2051-5960

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