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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography

Fig. 3

Representative images of automatic retinal layer segmentation from the control eye that did not receive any injection (top two rows) and the experimental eye that received intravitreal NMDA injection (bottom two rows). For each retinal OCT scan, the following ten layers were segmented and measured: combined inner limiting membrane and retinal nerve fiber layer (ILM-RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), external limiting membrane (ELM), photoreceptor layer (PRL), retinal pigment epithelium (RPE), and Bruch’s membrane (BM). The choroid is also labeled underneath BM. Scale bar = 100 μm. The auto-segmentation model was able to follow the blood vessel boundaries in the RNFL layer (white arrows) while avoiding the projection artifacts in the outer retinal layers (red arrow)

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