Fig. 1

GABRD and GPR162 expression in human brain a IHC analysis of the cortex, hippocampus, caudate and cerebellum. GABRD and GPR162 stained positively and strongly at a subset of neurons in the cortex, hippocampus, and less robustly in the caudate and cerebellum (n = 3). Scale bar = 100 μm. b Histone H3 was stained as internal control, and stained positively at nucleus, rather than other cellular components. Scale bar = 100 μm. c Histogram showed the expression abundance of markers in each brain region. *p < 0.05, **p < 0.01, ***p < 0.001, one-tailed nonparametric ANOVA followed by Kruskal–Wallis test