Fig. 8
From: The genomic alterations in glioblastoma influence the levels of CSF metabolites
Kaplan-Meier plots showing survival probability for 9 GBM, IDH-wildtype patients divided into “high” (in red) and “low” (in blue) metabolite level groups. A patient is classified as “high” if the individual metabolite level is above the cutoff value calculated by CutoffFinder and classified as “low” if below the cutoff. CSF levels of 2-methylbutyrylcarnitine, aminobutanal, and acetylcholine are all inversely associated with survival. (A) 2-methylbutyrylcarnitine (p = 0.046); median survival in days (High = 681, Low = N/A). (B) Aminobutanal (p = 0.022); median survival in days (High = 382, Low = N/A). (C) Acetylcholine (p = 0.022); median survival in days (High = 382, Low = N/A)