Fig. 1
From: Potential prognostic determinants for FET::CREB fusion-positive intracranial mesenchymal tumor
Representative images of MRI T1 post contrast (T1 + C), T2 FLAIR, H&E, and immunohistochemical stains for Cases 1–5. On MRI imaging, all five tumors were supratentorial, well-circumscribed, avidly enhancing lesions with surrounding vasogenic edema; however, on H&E stained sections, they showed heterogenous morphology. Cases 1 and 2 were composed of spindled/stellate tumor cells with a dense lymphocytic infiltrate, while Cases 3 and 4 featured sheets of epithelioid cells and highly-packed small round blue cells, respectively. Case 5 was distinct for its relatively low cellularity and a prominent myxoid stroma. By immunohistochemistry, desmin was positive in all cases except Case 5, and all five cases showed at least focal positivity for EMA