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Table 3 APOE genotype across all disease groups

From: Prevalence, distribution, and severity of cerebral amyloid angiopathy differ between Lewy body diseases and Alzheimer’s disease

APOE genotype

Overall N, (%)

AD N, (%)

DLB N, (%)

PDD N, (%)

PD N, (%)

Total n = 96

Total n = 62

Total n = 20

Total n = 10

Total n = 4

e2/2

1 (1.04)

1 (1.51)

(0.00)

(0.00)

0.00

e2/3

3 (3.13)

1 (1.51)

1 (5.00)

(0.00)

1 (25.00)

e2/4

3 (3.13)

2 (3.32)

(0.00)

1 (10.00)

0.00

e3/3

35 (36.50)

14 (22.60)

12 (60.00)

7 (70.00)

2 (50.00)

e3/4

47 (48.95)

37 (59.70)

7 (35.00)

2 (20.00)

1 (25.00)

e4/4

7 (7.29)

7 (11.36)

(0.00)

(0.00)

0.00

APOE allele presence

     

e2

(7.30)

(6.50)

(5.00)

(10.00)

(25.00)

e3

(88.50)

(83.90)

(100.00)

(90.00)

(100.00)

e4

(60)*†

(75.4)*†¶

(35.00)

(30.00)

(25.00)

  1. AD Alzheimer’s disease, DLB dementia with Lewy bodies, PDD Parkinson’s disease dementia, PD Parkinson’s disease
  2. *p < 0.05 using chi-square test
  3. *†e4 is associated with CAA severity in whole cohort and AD
  4. e4 is associated with presence of type 1 CAA in AD