Table 1 Demographics of cohort

case n

94

30

17

11

Age (± SE)

82.8 (± 0.91)

79.4 (± 0.91)

82.7 (± 1.63)

79.1 (± 2.94)

0.067

Sex (M:F)

45:49

23:7

12:5

9:2

p < 0.05^ab§

Braak NFT stage [8]

Braak IV = 1 Braak V = 5 Braak VI = 88

Braak I = 3 Braak II = 8 Braak III = 15 Braak IV = 4

Braak I = 2 Braak II = 2 Braak III = 11 Braak IV = 2

Braak I = 4 Braak II = 4 Braak III = 3

p < 0.001^c§

CERAD score [44]

B = 10 C = 84

negative = 17 A = 4 B = 7 C = 2

negative = 10

A = 4 B = 3

negative = 11

p < 0.001^de§

Thal Phase [55]

Thal 4 = 6 Thal 5 = 88

Thal 0 = 2 Thal 1 = 2 Thal 2 = 3 Thal 3 = 8 Thal 4 = 8 Thal 5 = 7

Thal 0 = 1 Thal 1 = 2 Thal 2 = 3 Thal 3 = 4 Thal 4 = 3 Thal 5 = 4

Thal 0 = 4 Thal 1 = 2 Thal 2 = 2 Thal 3 = 2 Thal 4 = 1

p < 0.001^f§

NIA-AA criteria [45]

Intermediate = 1 High = 93

Not = 2 Low = 15 Intermediate = 13

Not = 1 Low = 11 Intermediate = 5

Not = 4 Low = 6 Intermediate = 1

p < 0.001^gh§

McKeith criteria [42]

no LBD = 69 Brainstem = 2 Amygdala predominant = 23

Limbic = 4 Neocortical = 28

Limbic = 1 Neocortical = 16

Brainstem = 8 Limbic = 3

p < 0.001^ij§

Braak LB stage [9]

Braak 0 = 69 Braak 1 = 2 not classifiable = 23

Braak 4 = 4 Braak 5 = 1 Braak 6 = 25

Braak 4 = 1 Braak 5 = 3 Braak 6 = 13

Braak 2 = 3 Braak 3 = 5 Braak 4 = 3

p < 0.001^klm§