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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Regional differences in synaptic degeneration are linked to alpha-synuclein burden and axonal damage in Parkinson’s disease and dementia with Lewy bodies

Fig. 2

Representative images of synaptic puncta, NfL and pathological hallmarks in controls, PD, PDD, and DLB donors. Representative images of (A) synaptophysin+ pre-synaptic puncta, (B) SV2A+ pre-synaptic puncta, (C) NfL, (D) pSer129 α-synuclein, (E) amyloid-beta and (F) p-tau were acquired in the parahippocampal gyrus of controls, PD, PDD and DLB donors. Legend: DLB: Dementia with Lewy Bodies; NfL: neurofilament light chain; PD: Parkinson’s disease; PDD: Parkinson’s disease dementia; p-tau: phosphorylated tau

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Acta Neuropathologica Communications

ISSN: 2051-5960

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