Fig. 6

Neutralizing IFNγ attenuates Olig001-SYN mediated demyelination. A Same experiment design that was used in assessing neuroinflammation in Fig. 5. B Representative images of luxol fast blue staining displaying myelin within the striatum. Boxes in the bottom left are zooms of areas of demyelination highlighted in red. Red arrows point to areas of demyelination. (C) Myelin fold change between ipsi- and contra-lateral sides of the striatum and corpus collosum. Mean values ± SEM are plotted, non-parametric Wilcoxon test, *p < 0.05. For immunohistochemistry experiments, n = 3 per group. Each data point represents one mouse