Fig. 4

Nuclear area density of SNCA transcripts in neurons, oligodendrocytes, and astrocytes in controls. Box and whisker plots of nuclear area density of SNCA transcript area density in neurons in the substantia nigra (SN, n = 101) and amygdala (n = 112), oligodendrocytes in the pons (n = 113), and astrocytes in the amygdala (n = 105) in control cases. The nuclear area density of SNCA transcripts in neurons is significantly higher than those in oligodendrocytes and astrocytes (p < 0.001). The nuclear area density of SNCA transcripts in oligodendrocytes is significantly higher than that of astrocytes (p < 0.05). The upper and lower whiskers indicate the 95th percentile and 5th percentile, respectively. The top and bottom of the box indicate the first and third quartiles, respectively. The middle line splitting the box indicates the median. The small circles in the plots indicate outliers. For statistics, Kruskal–Wallis test and Dunn’s post hoc analysis with Bonferroni correction are used. Statistically significant findings where p < 0.05 and p < 0.001 are indicated as * and **, respectively