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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Genetic alterations that deregulate RB and PDGFRA signaling pathways drive tumor progression in IDH2-mutant astrocytoma

Fig. 3

Protein expression and drug sensitivity for associated protein inhibitors. A Immunohistochemistry of indicated proteins for initial tumor (YMG25P, left) and recurrent tumor (YMG25R, right). Bars, 50 µm. B Bar graphs indicating % positive stained cells for indicated proteins. C, D Relative cell viability following PDGFR inhibitor (C) and CDK4/6 inhibitor (D) treatment at day3. DMSO, control. *P < 0.05. Data are represented as the mean ± SEM

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